Genetic variation in small multigene families
نویسندگان
چکیده
منابع مشابه
Evolution in multigene families
We now know a lot about the dynamics of nucleotide substitutions within existing genes, but we’ve neglected one key component of molecular evolution. We haven’t talked about where new genes come from. It’s important to understand this phenomenon because, after all, new metabolic functions are likely to arise only when there are new genes that can perform them. It’s not likely that an existing g...
متن کاملMultigene Families: Evolution
Groups of genes showing similarity with each other are referred to as a gene family, arising from wholesale or partial gene duplication. The clustering of functionally related members of a gene family reflects their common ancestry and subsequent duplication and divergence. It has been speculated that gene duplication is essential for the creation of major evolutionary novelty. Genome projects ...
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The co-evolutionary arms race between host immune genes and parasite virulence genes is known as Red Queen dynamics. Temporal fluctuations in allele frequencies, or the 'turnover' of alleles at immune genes, are concordant with predictions of the Red Queen hypothesis. Such observations are often taken as evidence of host-parasite co-evolution. Here, we use computer simulations of the Major Hist...
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A simple two-locus gene conversion model is considered to investigate the amounts of DNA variation and linkage disequilibrium in small multigene families. The exact solutions for the expectations and variances of the amounts of variation within and between two loci are obtained. It is shown that gene conversion increases the amount of variation within each locus and decreases the amount of vari...
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The proteolytic machinery of chloroplasts and mitochondria in Arabidopsis consists primarily of three families of ATP-dependent proteases, Clp, Lon, and FtsH, and one family of ATP-independent proteases, DegP. However, the functional significance of the multiplicity of their genes is not clear. To test whether expression of specific isomers could be differently affected by growth conditions, we...
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ژورنال
عنوان ژورنال: Genetical Research
سال: 1981
ISSN: 0016-6723,1469-5073
DOI: 10.1017/s0016672300020115